name | Drug A (Example) |
Classification | Antidepressant (SSRI) |
Pharmacokinetics | Oral absorption: Rapid and complete. Metabolism: Primarily by the liver via CYP2D6. Half-life: Approximately 24 hours. Excretion: Primarily in urine as metabolites. |
suggested dosage | adult male 25 70kg | 10-20 mg daily, taken orally with or without food. | adult female 25 70kg | 10-20 mg daily, taken orally with or without food. | dosage notes | Dosage may need adjustment based on individual patient response and medical history. |
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indications | 1 | Major Depressive Disorder | 2 | Generalized Anxiety Disorder | 3 | Panic Disorder |
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Safety in pregnancy | Limited data; consult with a healthcare professional. Potential risks may exist. Avoid use during the first trimester if possible. |
Safety in breastfeeding | Small amounts of the drug may pass into breast milk. Consult with a healthcare professional. |
side effects | 1 | Nausea | 2 | Headache | 3 | Insomnia | 4 | Sexual dysfunction | 5 | Weight changes |
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alternatives | |
contraindications | 1 | Known hypersensitivity to the drug or its components. | 2 | Pre-existing severe liver problems. | 3 | Uncontrolled seizures |
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interactions | 1 | Other drugs that affect CYP2D6 (e.g., certain antidepressants, antiarrhythmics) | 2 | Alcohol |
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warnings and precautions | 1 | Monitor for suicidal ideation, especially in the first few weeks of treatment. | 2 | Avoid abrupt discontinuation of the medication; gradually taper off the dose to avoid withdrawal symptoms. | 3 | May affect cognitive function; avoid driving or operating machinery until effects are known. | 4 | Caution in patients with pre-existing cardiovascular conditions. |
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additional informations | 1 | Dosage adjustments may be needed in patients with renal or hepatic impairment. | 2 | Consider patient history of previous mental health issues. | 3 | Monitor for serotonin syndrome if used concurrently with other serotonergic agents. |
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mechanism of action | Inhibits serotonin reuptake in the presynaptic neuron, thereby increasing the synaptic concentration of serotonin. |
scaffold structure | |
dosage forms | |
route of administration | |