| name | Cefuroxime |
| classification | Cephalosporin antibiotic, Second generation |
| pharmacokinetics | Cefuroxime is well absorbed orally and is widely distributed throughout the body. It penetrates well into various tissues and fluids, including the cerebrospinal fluid (CSF) if inflammation allows. The drug is primarily eliminated renally as active metabolites. Metabolism varies based on renal function. Important factors such as age and kidney function significantly impact the half-life and clearance. |
| suggested dosage | | adults | The dosage varies significantly depending on the infection being treated and the patient's renal function. Consult a physician for accurate dosage recommendations for a specific patient. | | note | Weight and age are factors that can influence the required dosage but should not be the primary factor determining this. |
|
| indications | Cefuroxime is used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and some sexually transmitted infections. It is effective against a broad range of susceptible bacteria. |
| safety in pregnancy | Limited data is available on the use of cefuroxime during pregnancy. While it is generally considered to be relatively safe, it's important to discuss the potential risks and benefits of the antibiotic with a physician if you are pregnant or contemplating pregnancy. |
| safety in breastfeeding | Cefuroxime is excreted in breast milk in small amounts. The benefits of breastfeeding often outweigh the potential risks of small amounts of the drug entering the infant's system, but it is vital to discuss the risks with a healthcare professional. |
| side effects | | 1 | Nausea | | 2 | Vomiting | | 3 | Diarrhea | | 4 | Abdominal pain | | 5 | Headache | | 6 | Skin rash | | 7 | Pruritus (itching) | | 8 | Hypersensitivity reactions (rare but serious) | | 9 | Blood dyscrasias (rare) |
|
| alternatives | |
| contraindications | | 1 | Known hypersensitivity to cephalosporins or penicillins | | 2 | Severe renal impairment (requiring dosage adjustment or exclusion in some cases) | | 3 | History of allergic reactions to other drugs, especially antibiotics |
|
| interactions | Cefuroxime can interact with certain other medications, including anticoagulants, oral hypoglycemics, and other antibiotics. Consult a physician about all medications being taken to ensure no contraindications or interactions are present. |
| warnings and precautions | | 1 | Monitor for signs of allergic reactions like hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. | | 2 | Patients with pre-existing kidney problems may require adjustments to the dosage. | | 3 | Monitor renal function during treatment with cefuroxime. | | 4 | Use caution in patients with liver disease due to limited metabolic clearance information. |
|
| additional informations | The specific dosage and duration of treatment will be determined by the severity and location of the infection, as well as the patient's response to therapy and overall health. Patient history is vital for proper medication selection and administration. Avoid self-medicating with antibiotics. |
| patient specific considerations | A 25-year-old male weighing 70 kg presents a standard dosage range. However, precise dosage and duration of treatment must be determined by a healthcare professional considering individual patient factors like comorbidities and renal function. |
| disclaimer | This information is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment. |
