| name | Amoxicillin |
| classification | Penicillins, Beta-lactam antibiotics |
| pharmacokinetics | Amoxicillin is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are typically achieved within 1-2 hours after oral administration. The drug distributes widely throughout the body, including the tissues and fluids. It is primarily eliminated by renal excretion, with a half-life of approximately 1 hour. Renal impairment can significantly prolong the elimination half-life. |
| suggested dosage | | 1 | | age group | 25 years old | | route | oral | | infection severity | mild | | dosage | 250-500 mg every 8 hours |
| | 2 | | age group | 25 years old | | route | oral | | infection severity | moderate | | dosage | 500 mg every 8 hours |
| | 3 | | age group | 25 years old | | route | oral | | infection severity | severe | | dosage | 1000 mg every 8 hours |
| | 4 | | weight | 70 kg | | route | oral | | dosage | Based on infection severity and susceptibility, dosage may vary. Consult a physician. |
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| indications | Amoxicillin is used to treat bacterial infections of the respiratory tract, urinary tract, skin, and soft tissues. It is effective against a wide range of gram-positive and some gram-negative bacteria. |
| safety in pregnancy | Amoxicillin is generally considered safe during pregnancy, especially in the short-term and under the supervision of a healthcare provider. However, the potential risks and benefits should be carefully assessed by the physician. |
| safety in breastfeeding | Amoxicillin passes into breast milk in low concentrations. Generally, it's considered compatible with breastfeeding, but the infant should be observed for any adverse effects. |
| side effects | | 1 | Nausea | | 2 | Vomiting | | 3 | Diarrhea | | 4 | Abdominal pain | | 5 | Allergic reactions (rash, hives, itching, anaphylaxis) | | 6 | Headache | | 7 | Dizziness | | 8 | Superinfections (e.g., yeast infections) |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to penicillin or cephalosporins | | 2 | History of severe allergic reactions to other antibiotics |
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| interactions | | 1 | Other antibiotics | | 2 | Oral anticoagulants | | 3 | Probenecid | | 4 | Certain medications used to treat HIV |
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| warnings and precautions | | 1 | Monitor for signs of allergic reactions | | 2 | Monitor for signs of superinfections | | 3 | Do not use in patients with a known penicillin allergy without physician consultation | | 4 | Renal impairment may require dosage adjustments | | 5 | Do not use expired medication |
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| additional information | Always consult a physician or other qualified healthcare professional for appropriate diagnosis and treatment plan. The information provided here is not a substitute for professional medical advice. |
