| name | Tetracycline |
| classification | Antibiotic, Tetracycline Class |
| pharmacokinetics | | absorption | Variable, affected by food and other medications. Absorption may be poor when taken with milk products, antacids, or some other medications, requiring separation by at least 2 hours. Maximum absorption typically occurs 1-3 hours after administration. | | distribution | Wide distribution throughout the body, including the teeth and bones. | | metabolism | Metabolized in the liver. | | excretion | Excreted primarily in urine. |
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| suggested dosage | | adult | | typical range mg | 250-500mg every 6 hours for infections; 500mg twice daily or 1g twice daily. Individual dosages vary considerably depending on the infection and patient factors, such as kidney function. | | note | Always follow the prescription written by a qualified physician. |
| | note | This dosage is a general guideline and should be tailored to the specific patient's needs and conditions. Consult a healthcare professional for accurate dosage recommendations and proper administration. |
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| indications | Various bacterial infections; specifically, skin infections, respiratory infections, sexually transmitted infections, and others. |
| safety in pregnancy | Category D. Tetracycline is contraindicated during pregnancy, especially during the second and third trimesters, and in the first trimester its use is typically avoided due to potential adverse effects on the developing fetus. |
| safety in breastfeeding | Tetracycline may be excreted in breast milk. Its use during breastfeeding is generally not recommended due to potential, though generally low, risk to the infant. |
| side effects | | 1 | Gastrointestinal upset (nausea, vomiting, diarrhea) | | 2 | Photosensitivity (increased skin sensitivity to sunlight) | | 3 | Vaginal yeast infections | | 4 | Superinfections (e.g., fungal or yeast infections) | | 5 | Tooth discoloration (especially in children) | | 6 | Headache | | 7 | Dizziness | | 8 | Nervous system effects | | 9 | Discoloration of teeth in children |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to tetracyclines | | 2 | Severe liver or kidney disease | | 3 | Pregnancy | | 4 | Lactation (breastfeeding) |
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| interactions | | 1 | Antacids, iron supplements, and some other medications may reduce the absorption of tetracycline. | | 2 | Concurrent use with other medications, especially those affecting liver function, kidney function, or gut flora (including oral contraceptives), must be monitored carefully. |
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| warnings and precautions | Always take the drug according to instructions from your doctor or a health professional. Inform your doctor about any existing medical conditions, allergies, and all medications you're taking. Use caution in patients with impaired renal function. |
| additional informations | Tetracycline should be taken on an empty stomach, at least 1-2 hours before or after meals to maximize absorption. Store in a cool, dry place and away from direct sunlight. Do not crush or chew tablets or capsules, unless directed by your physician. |
