| name | Mupirocin Topical |
| classification | Antibiotic (topical) |
| pharmacokinetics | Mupirocin is a topical antibiotic that is primarily absorbed by the skin and only to a small extent into the systemic circulation. Peak concentrations occur within hours of application and are generally localized to the site of application. The drug is not extensively metabolized and is excreted primarily unchanged through the kidneys. |
| suggested dosage | Apply a thin film of ointment, cream, or solution to the affected area 2 to 3 times daily, as directed by a physician. Do not use more than prescribed, and avoid covering the area with a dressing unless advised by a healthcare professional. |
| indications | Mupirocin is indicated for the treatment of localized skin infections such as impetigo, cellulitis, and folliculitis. It can also be used for the prevention of surgical site infections in specific procedures. |
| safety in pregnancy | Limited data exists on the use of topical mupirocin during pregnancy. However, most studies suggest it is likely safe for topical use during pregnancy. It is advisable to consult with a physician to weigh the potential benefits against the potential risks. |
| safety in breastfeeding | Limited data exist on the use of topical mupirocin during breastfeeding. Although it is not expected to cause significant harm to the infant, it is prudent to consult a physician about the potential risks. |
| side effects | Common side effects include skin irritation, redness, pain, itching, and burning at the application site. These are usually mild and temporary. More serious, but rare, side effects can include allergic reactions, such as hives, swelling, or difficulty breathing. If these occur, discontinue use and seek immediate medical attention. Note that if a rash develops, the application should be discontinued. |
| alternatives | |
| contraindications | Hypersensitivity or allergy to mupirocin or any of its components. Use cautiously in individuals with a history of skin conditions or those with compromised skin integrity. |
| interactions | No significant drug interactions are known when mupirocin is used topically. However, it is essential to inform the healthcare provider about all medications being taken to avoid potential interactions. If other topical medications are being used, ensure a proper interval between applications. |
| warnings and precautions | Do not use on large areas of skin. Use caution in children and infants. Avoid contact with eyes, mucous membranes, and open wounds. Ensure proper hygiene when applying the medication. If symptoms worsen, or if new symptoms develop, discontinue use and consult a healthcare professional. |
| additional information | Mupirocin is generally well tolerated. However, if irritation or allergic reactions develop, discontinue use immediately and seek medical advice. Follow the instructions provided by your physician precisely and ensure that all other medications are disclosed. Complete the full course of treatment even if symptoms subside to ensure the infection is fully cleared. |
| patient profile | |
