| drug name | Zinc Pyrithione Shampoo |
| classification | Anti-dandruff shampoo, antifungal, anti-inflammatory (topical) |
| pharmacokinetics | Zinc pyrithione is a topical agent. It is applied to the scalp where it is thought to act directly on the fungal elements and inflammatory processes. It is not absorbed in significant amounts through the skin into the systemic circulation. Therefore, systemic pharmacokinetic properties are not applicable. |
| suggested dosage | Apply a small amount of shampoo to wet hair, massage into scalp, leave on for 2-5 minutes, and rinse thoroughly. Repeat as directed by the product instructions, usually 1-2 times per week or as needed. |
| indications | Treatment of seborrheic dermatitis, dandruff, and pityriasis capitis. May also be used in the management of other scalp conditions involving inflammation or yeast-like fungal overgrowth. |
| safety in pregnancy | Zinc pyrithione is considered possibly safe during pregnancy. There are no controlled studies specifically for pregnancy. It's usually used as a topical treatment, and the risk of systemic side effects is considered low, but consult a doctor for confirmation. |
| safety in breastfeeding | Zinc pyrithione is considered possibly safe during breastfeeding. As it's a topical treatment, the amount reaching the systemic circulation and thus the baby is believed to be minimal. Always consult with a doctor or a lactation consultant before use during breastfeeding. |
| side effects | | 1 | Mild skin irritation (e.g., redness, itching, burning) at the application site. These reactions are usually temporary and resolve with continued use. | | 2 | Allergic reactions (e.g., rash, hives) are possible although less frequent. | | 3 | In rare cases, hair follicle inflammation or hair loss (alopecia). This is less common than mild skin irritation. |
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| alternatives | |
| contraindications | Hypersensitivity or known allergy to zinc pyrithione or any of the ingredients in the shampoo. If irritation, rash, or other skin reaction occurs, discontinue use immediately and consult a healthcare professional. |
| interactions | No significant drug interactions are expected with zinc pyrithione shampoo. However, it's always best to inform your doctor about all medications and supplements you are using. |
| warnings and precautions | | 1 | Do not swallow. Keep out of reach of children. | | 2 | Avoid contact with eyes. If contact occurs, rinse immediately with plenty of water. | | 3 | If irritation persists or worsens, discontinue use and consult a healthcare professional. | | 4 | If you have any underlying health conditions, consult your doctor before using this shampoo. |
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| additional information | Zinc pyrithione shampoo is generally well-tolerated and effective. It is available over-the-counter and suitable for self-treatment of mild to moderate dandruff and seborrheic dermatitis. However, for severe cases or if symptoms persist, consult a dermatologist for diagnosis and treatment. |
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