| name | Polymethylmethacrylate (PMMA) Fillers |
| classification | Cosmetic filler |
| pharmacokinetics | PMMA fillers are not absorbed into the body. They remain in the injected site as a permanent filler. There are no significant pharmacokinetic processes involved. |
| suggested dosage | Dosage is determined by the treating physician based on the desired aesthetic outcome and the specific treatment area. There is no standard dosage. |
| indications | Used for aesthetic enhancement, including facial rejuvenation by filling wrinkles and depressions, adding volume to the lips or cheeks, or correcting facial asymmetry. |
| safety in pregnancy | Limited data on use in pregnancy; use is generally not recommended due to unknown effects on a developing fetus. Consult with a physician about potential risks. |
| safety in breastfeeding | Limited data on use during breastfeeding; use is not recommended due to the potential for the filler material to possibly enter breast milk. Consult with a physician about potential risks. |
| side effects | | 1 | Pain | | 2 | Redness | | 3 | Swelling | | 4 | Bruising | | 5 | Infection (rare) | | 6 | Nodules (lumps) | | 7 | Asymmetry | | 8 | Migratory pain | | 9 | Granulomas (immune response) | | 10 | Allergic reactions (rare) | | 11 | Necrosis (tissue death - rare) | | 12 | Changes in sensation (numbness, tingling) |
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| contraindications | | 1 | Known allergy to PMMA or any of its components | | 2 | Uncontrolled bleeding disorders | | 3 | Active infection at the injection site | | 4 | History of poor wound healing | | 5 | Severe coagulopathy or any underlying condition that increases risk of bleeding | | 6 | Pregnancy and breastfeeding | | 7 | Certain skin conditions (e.g., active dermatitis at the injection site) |
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| interactions | Limited interactions, primarily with other injectables that may cause additional swelling or complications. Consult with a physician if considering other filler treatments in the same area. |
| warnings and precautions | | 1 | Potential for unevenness, lumps, or other complications if not performed by qualified professional. | | 2 | Risk of granulomas (inflammation) or other reactions at the injection site. | | 3 | Serious complications (e.g., tissue death) are rare but possible. | | 4 | Careful patient selection is crucial to minimize risks. | | 5 | Follow-up appointments are essential for monitoring and addressing any potential issues. | | 6 | Do not apply any heat or cold packs to the treatment area without physician approval | | 7 | Discontinue use of blood thinners for a period before and after the procedure |
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| additional informations | | 1 | PMMA fillers are considered permanent, though not completely permanent as they may degrade over time. | | 2 | The use of PMMA fillers is only recommended by qualified professionals with specific training in injection techniques and patient assessment. Non-qualified people must not use this filler. | | 3 | Results vary depending on patient factors and individual response to the filler. | | 4 | Detailed patient history and physical examination are necessary before considering treatment. | | 5 | Consider alternative, reversible fillers for those seeking non-permanent or reversible cosmetic enhancement |
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| patient profile | |
