| name | Polyethylene Glycol (PEG) |
| Classification | Laxative, Osmotic |
| Pharmacokinetics | PEG is a non-absorbable polysaccharide. It draws water into the colon through osmosis, increasing stool bulk and softening it. This effect is primarily within the gastrointestinal tract. No significant systemic absorption is observed. |
| suggested dosage | | adult | The typical dosage ranges from 17 grams to 34 grams per use, though specific recommendations vary by brand and indication. Consult the medication's labeling for precise directions. | | male 25 70kg | 17-34 grams PEG solution as a single dose may be suitable, but consult with a physician to ensure the appropriate dosage for your condition. |
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| indications | | 1 | Constipation, including opioid-induced constipation | | 2 | Preparation for medical procedures requiring a clear bowel (e.g., colonoscopy) | | 3 | Bowel cleansing before surgery |
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| Safety in pregnancy | Limited data on use during pregnancy is available. Consult a doctor to determine the risk-benefit ratio if pregnant or planning to become pregnant. |
| Safety in breastfeeding | PEG is likely safe during breastfeeding, given its limited systemic absorption, however, consulting with a healthcare professional is recommended. |
| side effects | | 1 | Abdominal cramps | | 2 | Nausea | | 3 | Vomiting | | 4 | Diarrhea | | 5 | Dehydration (potential, especially with excessive or incorrect dosage) |
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| alternatives | | 1 | | | 2 | | name | Docusate sodium | | class | Stool softener |
| | 3 | | name | Lactulose | | class | Osmotic laxative |
| | 4 | | name | Senna | | class | Stimulant laxative |
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| contraindications | | 1 | Severe dehydration | | 2 | Known hypersensitivity to PEG | | 3 | Intestinal obstruction or perforation |
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| interactions | | 1 | Certain medications can affect bowel movements. Inform your doctor about any other medications you are taking. | | 2 | Some medications may interfere with PEG's ability to work. Inform your doctor or pharmacist about all medications and supplements you are using. |
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| warnings and precautions | | 1 | Adjust dosage based on individual needs and response. Monitor hydration status if using for a prolonged period. | | 2 | Patients with kidney problems may need adjusted dosage or monitoring. | | 3 | Do not use if the solution has changed color or has an unusual odor. Contact your pharmacist if this happens. | | 4 | Do not use this as a long-term treatment for constipation without consulting your physician. |
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| additional information | | 1 | PEG is available in various forms, including oral solution and oral powder. Follow the specific instructions for preparation provided with the product. | | 2 | Always ensure that the solution is properly diluted. Excessive concentration can cause significant gastrointestinal distress. | | 3 | Keep out of reach of children. |
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| patient specific considerations | | age | No specific age-related concerns are detailed for this medication. | | weight | Dosages are usually weight-independent, but monitoring for individual response is crucial. |
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| disclaimer | This information is intended for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment. |
