| name | Platelet-Rich Plasma (PRP) |
| classification | Regenerative medicine |
| pharmacokinetics | PRP is not a drug in the traditional sense. It is a preparation of concentrated platelets and growth factors derived from a patient's own blood. Traditional pharmacokinetic principles do not fully apply. The therapeutic effect is localized to the site of application due to the bioactive factors within the concentrated platelets. Systemic absorption and metabolism are minimal. |
| suggested dosage | Dosage varies significantly depending on the application. A healthcare professional must assess the appropriate volume and concentration of PRP based on the patient's needs and the treatment area. There is no standardized one-size-fits-all dose. |
| indications | | 1 | Wound healing | | 2 | Hair loss treatment | | 3 | Orthopedic conditions (e.g., osteoarthritis, tendonitis, ligament injuries) | | 4 | Dental procedures | | 5 | Sports medicine |
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| safety in pregnancy | Limited data available. PRP therapy is not routinely used during pregnancy. Discussion with a healthcare professional experienced in both reproductive health and regenerative medicine is crucial to evaluate potential risks to the fetus. |
| safety in breastfeeding | Limited data available. Discussion with a healthcare professional experienced in both lactation and regenerative medicine is essential before considering PRP therapy. |
| side effects | | 1 | Mild pain or bruising at the injection site | | 2 | Swelling | | 3 | Allergic reaction (rare) |
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| alternatives | | 1 | | | 2 | | name | Other biologics | | description | e.g., growth factors or platelet lysate products |
| | 3 | | name | Physical Therapy | | description | Treatments like exercise and stretching can be helpful in some cases, especially as preventative measures |
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| contraindications | | 1 | Bleeding disorders | | 2 | Active infections at the treatment site | | 3 | Certain medical conditions requiring careful evaluation (e.g., uncontrolled blood pressure, coagulopathy) | | 4 | Areas of active infection or inflammation |
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| interactions | No significant drug interactions are known. However, patients taking anticoagulants should inform their physician as dose adjustments may be necessary. |
| warnings and precautions | A comprehensive medical evaluation is necessary to identify potential contraindications and address underlying health concerns. Proper technique is critical to avoid complications. Seek treatment only from qualified medical professionals. |
| additional information | PRP therapy is not a quick fix. Results vary based on the individual and the specific condition. Patience and realistic expectations are important for positive outcomes. A provider with extensive experience is recommended. |
| patient specific considerations | | age | Age 25 is a relatively healthy age for considering PRP therapy. Risk/benefit considerations should be discussed. | | weight | Patient weight (70kg) is not a direct contraindication. Appropriate dosage is determined by the physician. | | gender | Gender (male) is not a direct contraindication. Considerations will vary based on the application. | | medical history | A complete medical history is essential for safety. |
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| references | |
