| name | Mometasone |
| classification | Corticosteroid, Topical |
| pharmacokinetics | Mometasone furoate is a synthetic corticosteroid that is well absorbed through the skin. The absorption is influenced by the site of application, concentration, and duration of use. It is primarily metabolized in the liver and the metabolites are excreted in the urine and feces. Systemic absorption is generally low with topical application, but it can be higher with occlusive dressings or extensive application. Plasma protein binding is high. The exact pharmacokinetic parameters can vary based on the formulation and individual patient factors. |
| suggested dosage | Dosage of topical mometasone furoate is highly variable and dependent on the specific condition being treated and the affected area. It should be administered as directed by a healthcare professional. Generally, a thin film of the topical preparation is applied to the affected area once or twice daily. Do not use occlusive dressings unless directed by a doctor. |
| indications | Mometasone furoate topical is used for the treatment of inflammatory and pruritic dermatoses such as eczema, dermatitis, and psoriasis. It can also be used for allergic skin reactions. Consult a dermatologist or other qualified healthcare professional for specific indications. |
| safety in pregnancy | Limited data is available on the safety of mometasone furoate during pregnancy. Although systemic absorption is low, it is prudent to use the lowest effective dose for the shortest duration possible. Discuss any concerns about pregnancy with your doctor before using this medication. Avoid use during the first trimester unless clearly necessary. Consult your healthcare provider for tailored advice. |
| safety in breastfeeding | Mometasone furoate is potentially transferred into breast milk at low levels. The potential risk to a nursing infant is likely to be minimal at recommended dosages, but consult your doctor to ensure it's appropriate for you. |
| side effects | | 1 | Local skin reactions (e.g., burning, stinging, irritation, dryness, redness) | | 2 | Skin atrophy (thinning of the skin) | | 3 | Telangiectasia (reddened, dilated blood vessels) | | 4 | Striae (stretch marks) | | 5 | Acneiform eruptions | | 6 | Systemic side effects (rare but possible): These would be more prevalent with high or prolonged use or systemic absorption from extensive affected areas, particularly if applied on large skin areas or with occlusive dressings. Examples include Cushingoid syndrome, adrenal insufficiency, hyperglycemia, and others. |
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| alternatives | |
| contraindications | Patients with known hypersensitivity to mometasone or other corticosteroids, or other topical ingredients. Avoid use in active skin infections. Do not use with occlusive dressings unless directed by your doctor. |
| interactions | No significant interactions are documented with other drugs for typical topical use. Interactions may occur if the drug is absorbed systemically. Always inform your doctor of all medications, supplements and herbs you are taking. |
| warnings and precautions | | 1 | Use only as directed by a healthcare professional. | | 2 | Do not use on large areas of skin for extended periods. | | 3 | Stop use and consult your doctor if symptoms worsen or new symptoms develop. | | 4 | Avoid application to the eyes, mucous membranes, or open wounds. | | 5 | Monitor for signs of potential systemic effects, especially in patients with underlying conditions like diabetes or cardiovascular disease. | | 6 | Do not use in children without specific medical guidance. |
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| additional informations | Age and weight are not relevant factors in determining topical steroid dosage for routine use in this case, as this is a local application. |
| patient information | |
