| drug name | Ivermectin (topical) |
| classification | Antiparasitic, Anti-inflammatory (in some formulations) |
| pharmacokinetics | Topical application results in localized action with limited systemic absorption. The exact pharmacokinetics are formulation-dependent. Absorption through skin varies greatly depending on formulation, concentration, and site of application. Metabolism primarily occurs in the liver, and excretion is primarily via the liver and biliary route. Limited systemic data are available. |
| suggested dosage | Dosage information is not readily available for topical ivermectin. **Crucially, the dosage and application method for topical ivermectin should be strictly followed per the product's specific instructions and instructions from a healthcare professional. Self-treating with topical ivermectin is not recommended.** Dosage varies based on the specific indication and formulation. |
| indications | Topical ivermectin is primarily used for the treatment of skin conditions caused by certain parasites, such as scabies and rosacea. Consult a doctor. |
| safety in pregnancy | Limited data are available. **Consult with a healthcare professional before use during pregnancy.** Potential risks to the developing fetus need to be considered. |
| safety in breastfeeding | Limited data are available. **Consult with a healthcare professional before use while breastfeeding.** Potential risks to the infant need to be considered. |
| side effects | | 1 | Skin irritation | | 2 | Burning sensation | | 3 | Pruritus (itching) | | 4 | Erythema (redness) | | 5 | Local pain | | 6 | Edema (swelling) | | 7 | In rare cases, systemic effects (due to skin absorption) can occur. This needs the assessment of a physician. |
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| alternatives | | 1 | Permethrin (topical) | | 2 | Other topical antiparasitics (e.g., benzyl benzoate) | | 3 | Oral medications for specific parasitic infections if systemic issues exist. |
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| contraindications | | 1 | Known hypersensitivity to ivermectin or any component of the formulation. | | 2 | Open skin wounds or lesions at the application site. |
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| interactions | Limited interaction data available. **Important to inform your physician about all medications and supplements you are using.** |
| warnings and precautions | | 1 | Follow all instructions from the product label and your healthcare professional carefully. Do not exceed recommended dosage or use for longer than prescribed. | | 2 | Monitor the skin reaction closely. If any adverse reaction occurs, discontinue use and contact a physician immediately. | | 3 | Avoid contact with eyes. | | 4 | Topical application should only be used as directed by a medical professional. Topical ivermectin use for conditions other than those specified on the drug label may be inappropriate and/or dangerous. | | 5 | Always wash the application area thoroughly after use, following label instructions. |
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| additional information | Patient age and weight are not relevant factors in determining topical ivermectin dosage. Patient-specific factors and the nature of the skin condition need to be considered. Consult with a healthcare professional to determine the most suitable treatment. |
| patient specific details | | 1 | | parameter | Age | | value | 25 | | unit | years | | relevance | Not a significant factor for determining topical ivermectin dosage. |
| | 2 | | parameter | Weight | | value | 70 | | unit | kg | | relevance | Not a significant factor for determining topical ivermectin dosage. |
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