| name | Fluticasone Propionate Topical Cream |
| classification | Corticosteroid, Topical |
| pharmacokinetics | Fluticasone propionate is a corticosteroid primarily applied topically. It is absorbed through the skin, with generally low systemic absorption that can vary based on application extent, skin condition, and concentration. Metabolism occurs primarily in the liver, and elimination is primarily through urine and feces. Specific pharmacokinetic data for a 25-year-old male weighing 70 kg is not readily available in a general format. Topical application is intended to minimize systemic effects, but prolonged or extensive use can increase risk. |
| dosage | | description | Dosage is dependent on the specific condition being treated. Consult a physician for appropriate dosing instructions. | | example | For general inflammatory skin conditions, 1-2 applications daily may be used. The amount used per application should be determined by the affected area and severity. |
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| indications | Used to treat inflammatory skin conditions like eczema, contact dermatitis, and localized skin conditions characterized by redness, swelling, itching, and inflammation. Also used for psoriasis. |
| safety in pregnancy | Limited data exists. Avoidance, especially in the first trimester, is generally recommended. Consult a physician for specific guidance and risk/benefit assessment. |
| safety in breastfeeding | Limited data exists. Systemic absorption is low, and theoretical minimal transfer to breast milk is assumed, but not consistently confirmed. Consult a physician for appropriate guidance and risk/benefit assessment. |
| side effects | | 1 | | type | Local | | examples | | 1 | Burning | | 2 | Itching | | 3 | Skin irritation | | 4 | Dryness | | 5 | Redness |
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| | 2 | | type | Systemic | | description | Possible but unlikely at typical dosages for topical use. Risk increases with extensive use on large areas or prolonged use. | | potential examples | Effects related to increased, though low, systemic corticosteroid levels. Rare cases of systemic side effects can occur. |
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| contraindications | Hypersensitivity to fluticasone propionate or other corticosteroids. Do not use on open wounds or broken skin. |
| interactions | Potential interactions with other topical medications. Inform your doctor of all medications. |
| warnings and precautions | | 1 | Do not use for prolonged periods without consulting a doctor. | | 2 | If symptoms worsen or do not improve, discontinue use and seek medical attention. | | 3 | Avoid application to eyes or mucous membranes. | | 4 | Use only as directed by a physician. |
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| additional information | Fluticasone propionate is a potent corticosteroid. Proper application is crucial. Consult your physician if you have concerns. |
