| name | EllaOne (Ulipristal acetate) |
| Classification | Emergency Contraceptive |
| Pharmacokinetics | Ulipristal acetate is rapidly absorbed after oral administration. Peak plasma concentrations are reached within 1-2 hours. The drug is primarily metabolized in the liver and eliminated in the urine. The half-life is approximately 30 hours, allowing for a single dose. |
| suggested dosage | A single dose of 30mg ulipristal acetate as a tablet taken orally as soon as possible within 120 hours (5 days) of unprotected intercourse. If vomiting occurs within 3 hours of taking the medication, a repeat dose may be needed. |
| indications | Emergency contraception to prevent pregnancy after unprotected intercourse. |
| safety in pregnancy | Not indicated for use in pregnancy. If pregnancy does occur, there is no evidence to suggest harm to the developing fetus from ulipristal acetate. |
| safety in breastfeeding | Ulipristal acetate is generally considered compatible with breastfeeding; however, limited data is available, and therefore caution is recommended. The amount of ulipristal acetate that passes into breast milk is unknown. If breastfeeding, consult your healthcare provider. |
| side effects | | 1 | Nausea (most common) | | 2 | Headache | | 3 | Fatigue | | 4 | Abdominal pain | | 5 | Dizziness | | 6 | Breast tenderness | | 7 | Changes in menstrual bleeding (e.g., spotting, delayed or prolonged bleeding) | | 8 | Vomiting | | 9 | Diarrhea |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to ulipristal acetate or any of its inactive ingredients. | | 2 | Severe liver disease |
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| interactions | | 1 | Limited drug interactions are known. Ulipristal acetate may influence the metabolism of some drugs; however, more data is needed for a comprehensive picture. | | 2 | Avoid concomitant use with strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) as these can increase ulipristal acetate levels. |
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| warnings and precautions | | 1 | Not suitable for regular use as a contraceptive method. | | 2 | Effectiveness is reduced when taken later after unprotected intercourse. | | 3 | Consult a healthcare professional if there is concern about side effects or if you have underlying health conditions. | | 4 | May not be suitable for women with a history of migraines, or with certain cardiac conditions. A healthcare professional should be consulted. |
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| additional information | | 1 | Effectiveness is highest when taken as early as possible after unprotected sex. | | 2 | Does not protect against sexually transmitted infections (STIs). | | 3 | For women with persistent or severe side effects, a healthcare provider should be consulted | | 4 | It is important to understand the appropriate use and potential side effects before taking EllaOne. | | 5 | This information is for general knowledge and does not constitute medical advice. Consult with a healthcare provider for any health concerns or before making any decisions related to your health or treatment. |
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