| name | Clobetasol Propionate 0.05% |
| classification | Topical corticosteroid, potent |
| pharmacokinetics | Clobetasol propionate is a potent corticosteroid that is primarily absorbed through the skin. Systemic absorption is generally low with topical application, but can be higher with occlusive dressings or in areas of damaged skin. Metabolism occurs primarily in the liver, and excretion is primarily in the urine. |
| suggested dosage | Apply a thin film to the affected area once or twice daily. Follow the directions on the prescription label and consult with a dermatologist for specific dosage recommendations. Do not exceed the prescribed dosage. |
| indications | Used for the treatment of inflammatory skin conditions, such as atopic dermatitis, psoriasis, and eczemas. May be used for localized inflammatory conditions like contact dermatitis, allergic reactions, or insect bites. |
| safety in pregnancy | Limited data on human use during pregnancy. Topical corticosteroids are generally considered to be relatively safe if used appropriately and in accordance with the physician's guidance; however, the potential risks and benefits should be carefully considered. Consult with your doctor. |
| safety in breastfeeding | Limited data. Topical corticosteroids are generally considered to be relatively safe when used as directed; however, the potential risks and benefits should be carefully considered. Consult with your doctor. |
| side effects | | 1 | Skin irritation | | 2 | Burning | | 3 | Stinging | | 4 | Thinning of the skin (atrophy) | | 5 | Striae (stretch marks) | | 6 | Skin discoloration | | 7 | Telangiectasia (small dilated blood vessels) | | 8 | Hirsutism (excessive hair growth) | | 9 | Acne | | 10 | Fungal or bacterial skin infections |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity or allergy to clobetasol propionate or other topical corticosteroids | | 2 | Active skin infections (unless specifically indicated by the physician) | | 3 | Use over large areas of skin for prolonged periods | | 4 | Use on face, or other sensitive areas, for a prolonged duration without direct supervision of a physician |
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| interactions | | 1 | May interact with other topical medications. Inform your physician about any medications you are currently taking. | | 2 | Avoid use with other topical corticosteroids |
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| warnings and precautions | | 1 | Do not use on damaged, broken, or infected skin. | | 2 | Do not use occlusive dressings unless advised by a physician. | | 3 | Avoid contact with the eyes, mouth, or mucous membranes. | | 4 | Monitor for signs of skin thinning or atrophy, especially with prolonged use. | | 5 | Do not use on the face unless advised by a physician. | | 6 | Never use this medication on areas not prescribed. | | 7 | Discontinue use and contact your physician if symptoms worsen or do not improve after a few days. |
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| additional informations | | 1 | Important to follow the doctor’s instructions accurately to avoid potential complications. | | 2 | Use only the prescribed amount. Do not use more or less without checking with the doctor first. | | 3 | Store the medication in a cool dry place away from sunlight. |
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| patient profile | |
