Carbapenems E G Meropenem Imipenem

Drug Overview

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drug classCarbapenems
patient details
age25
weight70
sexMale
drugs
1
nameMeropenem
ClassificationCarbapenem antibiotic
Pharmacokinetics
absorptionAdministered intravenously or intramuscularly. Good absorption.
distributionWide distribution throughout the body, including cerebrospinal fluid (CSF) with adequate penetration.
metabolismMetabolized primarily by the kidneys.
excretionExcreted primarily by the kidneys as unchanged drug or as metabolites.
suggested dosageDosage varies based on the severity of infection and patient factors. Consult a physician for appropriate dosage.
indicationsTreatment of serious bacterial infections, including pneumonia, skin and soft tissue infections, urinary tract infections, intra-abdominal infections, and complicated infections.
Safety pregnancyLimited data available; use only when potential benefit outweighs potential risks to the fetus. Discuss with a healthcare professional.
Safety breastfeedingLow concentrations in breast milk. Use with caution if breastfeeding. Discuss with a healthcare professional.
side effects
1Nausea
2Vomiting
3Diarrhea
4Headache
5Seizures (especially with high doses or in patients with pre-existing seizure disorders or head injury)
6Allergic reactions
7Hypotension (low blood pressure)
8Superinfection (fungal or other bacterial infections)
9Transaminitis(Liver inflammation)
10Nephrotoxicity (Kidney damage)
alternatives
1Imipenem
2Ertapenem
3Doripenem
4Ceftriaxone
5Cefepime
contraindicationsHypersensitivity to carbapenems or other components of the drug.
interactionsMay interact with other medications, including nephrotoxic drugs. Consult a healthcare professional.
warnings precautions
1Monitor kidney function during therapy and adjust dosage as needed.
2Use cautiously in patients with liver or kidney dysfunction.
3Seizure precautions may be needed, especially in patients with a history of seizures or other neurological conditions.
4Monitor for signs of allergic reactions.
5Closely monitor patients for development of superinfection.
additional informationsShould be administered with caution to patients with a history of seizures or neurological conditions. Monitor the patient's condition closely. Appropriate doses and route of administration should be individualized.
Other Important FieldsAlways seek professional medical advice before use or change in dosage.
2
nameImipenem
ClassificationCarbapenem antibiotic
detailsImipenem is typically given in combination with cilastatin (a drug that protects the kidneys from imipenem's nephrotoxicity).
general warningsAlways consult a healthcare professional for appropriate diagnosis and treatment of infections. These details are for informational purposes only and do not constitute medical advice.
DisclaimerInformation provided is for general knowledge and informational purposes only. This is not a substitute for professional medical advice. Consult a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

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Reference Patient:(25 years,Male, 70KGs) *Not a medical advice

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