name | Meropenem |
Classification | Carbapenem antibiotic |
Pharmacokinetics | absorption | Administered intravenously or intramuscularly. Good absorption. | distribution | Wide distribution throughout the body, including cerebrospinal fluid (CSF) with adequate penetration. | metabolism | Metabolized primarily by the kidneys. | excretion | Excreted primarily by the kidneys as unchanged drug or as metabolites. |
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suggested dosage | Dosage varies based on the severity of infection and patient factors. Consult a physician for appropriate dosage. |
indications | Treatment of serious bacterial infections, including pneumonia, skin and soft tissue infections, urinary tract infections, intra-abdominal infections, and complicated infections. |
Safety pregnancy | Limited data available; use only when potential benefit outweighs potential risks to the fetus. Discuss with a healthcare professional. |
Safety breastfeeding | Low concentrations in breast milk. Use with caution if breastfeeding. Discuss with a healthcare professional. |
side effects | 1 | Nausea | 2 | Vomiting | 3 | Diarrhea | 4 | Headache | 5 | Seizures (especially with high doses or in patients with pre-existing seizure disorders or head injury) | 6 | Allergic reactions | 7 | Hypotension (low blood pressure) | 8 | Superinfection (fungal or other bacterial infections) | 9 | Transaminitis(Liver inflammation) | 10 | Nephrotoxicity (Kidney damage) |
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alternatives | |
contraindications | Hypersensitivity to carbapenems or other components of the drug. |
interactions | May interact with other medications, including nephrotoxic drugs. Consult a healthcare professional. |
warnings precautions | 1 | Monitor kidney function during therapy and adjust dosage as needed. | 2 | Use cautiously in patients with liver or kidney dysfunction. | 3 | Seizure precautions may be needed, especially in patients with a history of seizures or other neurological conditions. | 4 | Monitor for signs of allergic reactions. | 5 | Closely monitor patients for development of superinfection. |
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additional informations | Should be administered with caution to patients with a history of seizures or neurological conditions. Monitor the patient's condition closely. Appropriate doses and route of administration should be individualized. |
Other Important Fields | Always seek professional medical advice before use or change in dosage. |