drug | Beta-Alanine |
name | Beta-Alanine |
classification | Dietary supplement, potentially a nootropic agent in some contexts |
pharmacokinetics | Beta-alanine is readily absorbed from the gastrointestinal tract. It is metabolized into carnosine, which is a dipeptide that is stored primarily in skeletal muscle. Elimination is primarily via the kidneys. The half-life of beta-alanine is not consistently reported, varying with dosage and the individual, but its impact on carnosine levels generally manifests gradually. |
suggested dosage | male 25 70kg | typical range | 2-5 grams per day, potentially in divided doses, although most research uses doses between 4 and 8 grams per day | notes | Consult with a healthcare professional to determine the appropriate dosage based on individual needs and goals. Higher doses are often used in athletic contexts to improve performance, but are typically not recommended for everyday use unless directed by a healthcare professional. |
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indications | 1 | Potential improvement in exercise performance (especially high-intensity and short-duration exercise), possibly through increased carnosine levels in muscle tissue. | 2 | Potential benefits for muscle endurance and strength during exercise. | 3 | Some research suggests potential role in managing symptoms of burning mouth syndrome (BMS). | 4 | Potential role in reducing symptoms of osteoarthritis and fibromyalgia | 5 | Used in some cases as a nootropic agent, but evidence is limited. |
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safety in pregnancy | Limited data available. Consult with a healthcare professional regarding the safety of use during pregnancy. |
safety in breastfeeding | Limited data available. Consult with a healthcare professional regarding the safety of use during breastfeeding. |
side effects | 1 | Tingling or prickling sensation (paresthesia), usually mild and temporary, often reported at higher doses. | 2 | Possible gastrointestinal effects such as nausea, diarrhea, or stomach upset at higher doses. | 3 | Rare reports of skin rashes or allergic reactions. | 4 | Uncommon, but potentially severe, interactions with other medications. |
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alternatives | 1 | Other nootropics (e.g., caffeine, creatine, L-theanine) | 2 | Other dietary supplements with purported athletic enhancement capabilities (consider with medical advice) | 3 | Other treatments for underlying conditions that may be related to symptoms the patient is experiencing |
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contraindications | 1 | Individuals with known hypersensitivity or allergy to beta-alanine or related substances. | 2 | Individuals with pre-existing kidney problems (caution is advised). |
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interactions | Potentially interacts with certain medications; consult with a physician before use, especially if taking other medications. |
warnings and precautions | 1 | May cause paresthesia, usually mild, temporary and not concerning. | 2 | Start with a low dose and gradually increase, if necessary, under the supervision of a healthcare professional to minimize potential side effects. | 3 | May increase risk of kidney stone formation if taken in high doses or with insufficient hydration. | 4 | Not suitable for everyone. Consult a healthcare professional, especially for individuals with specific health conditions or concerns. | 5 | Do not self-treat or increase dosage without medical advice |
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additional informations | Beta-alanine's effects are primarily on muscle tissue carnosine levels, which influences exercise performance in specific circumstances. It is important to be fully aware of the scientific evidence and limitations before relying on supplements. |
dosage form | Typically available as powders, capsules, tablets, and chews. |