name | AbobotulinumtoxinA |
classification | Neurotoxin; Botulinum Toxin Type A |
pharmacokinetics | Poorly absorbed after subcutaneous injection; primarily distributed in injected muscles; degraded primarily via enzymatic mechanisms. |
dosage | Variable; depends on indication and physician judgment. Requires individual assessment. |
indications | 1 | Chronic migraine prevention | 2 | Hyperhidrosis | 3 | Blepharospasm | 4 | Cervical dystonia | 5 | Strabismus | 6 | Spasmodic dysphonia |
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pregnancy safety | Limited data; use not recommended unless benefit outweighs risk; consult healthcare professional. |
breastfeeding safety | Limited data; use not recommended unless benefit outweighs risk; consult healthcare professional. |
side effects | 1 | Local reactions (pain, swelling, bruising) | 2 | Headache | 3 | Fatigue | 4 | Dry mouth | 5 | Muscle weakness (temporary) | 6 | Double vision | 7 | Dysphagia | 8 | Hoarseness | 9 | Nausea | 10 | Vomiting | 11 | Flushing |
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alternative drugs | 1 | | 2 | name | Rituximab | class | Immunosuppressant |
| 3 | name | Etanercept | class | Tumor Necrosis Factor (TNF) Inhibitor |
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contraindications | 1 | Hypersensitivity to botulinum toxins/formulation components | 2 | Active injection site infection | 3 | Inability to provide informed consent |
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drug interactions | Limited reported interactions; use caution with medications affecting neuromuscular transmission; consult physician. |
warnings and precautions | 1 | Administered by qualified healthcare professional. | 2 | Monitor patient closely post-injection, especially for muscle weakness. | 3 | Use cautiously in patients with neuromuscular disorders (e.g., myasthenia gravis). | 4 | Use cautiously in patients with a history of stroke. |
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additional information | Individualized treatment crucial; specific indication, patient condition, and age guide dosage and regimen. |
patient data | |
disclaimer | This information is for general knowledge and does not constitute medical advice. Always consult with a qualified healthcare professional. |